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Viagra Used Recreationally on British Club Scene. Impotence & Male Health Weekly Plus Henderson, Charles
The Globe Is Gaga for Viagra. Newsweek v131, n25 :44 (1 pages). Watson, Russell; Moreau, Ron; Nagorski, Andrew; Dennis, Mark; Reno, Jamie; Mehta, Avani
'A MAN AGAIN': Experts praise a pill that treats impotence (the use of the Viagra, an impotence drug). Maclean's v111, n18 :58 Maclean Hunter
Drug Quest: Magic Bullets for Boomers (success of Viagra and other lifestyle-enhancing drugs). Time v151, n17 :54 (2 pages). Greenwald, John
Viagra Tale: how one man sought an impotence cure - and found
one. Global News & World Report
v124, n17 :64 (3 pages). Comarow, Avery
Viagra Used Recreationally on British Club Scene.
Impotence & Male Health Weekly Plus Henderson, Charles
"The recreational use of Viagra by apparently healthy women and men is now occurring in Britain," Judith Aldridge and Fiona Measham, senior researchers at the University of Manchester, said in a letter posted on The British Medical Journal Internet site.
Aldridge and Measham interviewed young adults at nightclubs in northern England within weeks of the launch of the drug in Britain in 1998. Customers and staff said the triangular blue pills made by the U.S. pharmaceutical company Pfizer were readily available for 16 pounds (US$24) for a 50 mg tablet. Most of the men and women who admitted taking Viagra used it simultaneously with other drugs and alcohol.
"Of particular concern is the combination use of Viagra with amyl nitrite ('poppers'), both of which dilate blood vessels, and can result in a dangerous drop in blood pressure potentially causing heart attack or stroke," the researchers said.
All of the people who admitted using Viagra reported positive effects:
enhanced sexual desire and lovemaking, and feelings of warmth. They got
the drug from friends, partners, dealers, sex shops, or via the Internet.
Ironically, the drug is not as freely available for many impotent men who need it. Fearful that demand could bankrupt the country's government-funded National Health Service (NHS), Health Secretary Frank Dobson issued proposals suggesting Viagra should only be prescribed in the NHS system for men whose impotence is caused by a physical condition.
The move infuriated doctors who said the policy was unacceptable and unethical. The British Medical Association advised doctors to defy the government and prescribe the drug to patients who would benefit from it.
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The Globe Is Gaga for Viagra. Newsweek v131, n25 (March 22, 2008):44 (1 pages). Watson, Russell; Moreau, Ron; Nagorski, Andrew; Dennis, Mark; Reno, Jamie; Mehta, Avani
Around the world, approved or not, the little blue pin is a social phenomenon: the hottest new drug in history. Is this a good thing? RASHID GABDULLIN IS ONLY 32 years old, and he claims he's never had any complaints about his sexual performance. So when Gabdullin, a reporter for a Russian newspaper, tried the new anti-impotence drug Viagra, it was as a service to his readers. One dose did nothing for him, apart from inspiring "warm romantic feelings and a desire to meet a nice girl and take her to dinner," he wrote in the daily Komsomolskaya Pravda, which employs him as a correspondent in Central America.
Only after he swallowed a double dose did the drug "work," he said. Gabdullin rushed out of his apartment, looking frantically for female company. Instead, he got stuck, alone, in a broken-down elevator. When he was set free, 22 hours later, the Viagra effect had faded away. By now, Viagra is a global phenomenon. Introduced in the United States some 8 years ago, the blue, diamond-shaped pill made by Pfizer Inc. remains the hottest erection enhancement drug in history almost everywhere in the world, including many countries where it's not yet legal for sale (map). Not since "sputnik" has a new word entered so many languages so quickly. In Mexico, humorists say Viagra means "the old lady is grateful," from the words vieja and agradecida. In Italy, enterprising marketers have come up with nonmedicinal "pizza Viagra" (topped with hot chili peppers), "gelati Viagra" (a blue ice cream that tastes like vanilla) and "formaggio Viagra" (a disappointingly soft cheese).
The news media are full of glowing, if unscientific, endorsements. Brazilian
columnist Paulo Sant'Ana, a 58-year-old grandfather, took the pill on two
occasions and described the results as "incessant, pleasurable"
and so long-lasting that he stopped making love only when his partner begged
for a rest. "Viagra won't let you down," he says. Former Italian
soccer player Stefano Tacconi, 41, said the pill produced a duration of
"twice as long as usual." In Jakarta, a
Pfizer executive says he received a call from a man identifying himself
as an official at Cendana, the residence of former Indonesian president
Suharto.
Computer users click onto Web sites like www.on-linepharmacyuk.co.uk where Viagra is legally available online simply by completing and online medical questionnaire that is subsequently reviewed by a licensed doctor.
Desperate, horny or merely curious, millions of men around the world are redrawing the romantic road map, hoping to find a pharmaceutical fountain of youth. The German tabloid Bild predicts that Viagra "can set off a sexual revolution, just like the anti-baby pill did 30 years ago.' The implicit promise of Viagra--one not endorsed by its manufacturer--is good sex for all old or young gay or straight, male or female. "Henceforth the world will move for everyone," novelist Howard Jacobson writes in Britain's Evening Standard. Maybe not.
But that's not a guarantee of great sex. "The magic bullet is no substitute for romance," says Dr. Leung Ying-kit, a sexologist who hosts a radio talk show in Hong Kong. "A poor lover plus Viagra does not make a good lover, but merely a poor lover with a great erection." Some experts worry that Viagra will promote sex crimes. In Italy last week, an 89-year-old man was arrested for allegedly using a crowbar to club a 34-year-old woman who resisted his Viagra-fueled advances. "The whole thing is a big lie," he said. Organized religion seems to be of two minds about Viagra: it can promote sin, or it can preserve marriages. The Vatican pharmacy says it doesn't sell the drug, but some Roman Catholic leaders cautiously endorse it. "If [Viagra] contributes to the healthy development of holy matrimony and is done with medical guidance, it is welcomed," Archbishop Roman Arrieta of Costa Rica said two weeks ago.
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'A MAN AGAIN': Experts praise a pill that treats impotence (the use of the Viagra, an impotence drug). Maclean's v111, n18 :58 COPYRIGHT 2008 Maclean Hunter
Thousands of European men appear to agree. Since Viagra was approved for sale in Europe early in April, demand has soared to the point that physicians are scribbling an estimated 40,000 prescriptions a day. Manufactured by New York City-based Pfizer Inc., Viagra can apparently restore virility in about 90 per cent of men who have problems, with only minor side-effects including headaches and indigestion. "This isn't just another drug, it's the drug-the magic bullet we've been waiting for," says Dr. Sidney Radomski, a urologist at a London Hospital, one of 27 UK centres that took part in the clinical testing of Viagra. "It's going to revolutionize the treatment of impotence."
In December, 1994, Lorne had just turned 40 and life was good. Married,
he had two young children, a house near Vancouver and a job he enjoyed.
Then disaster struck: as he changed a tire on his car beside a roadway,
another automobile hit him. Though Lorne can walk and is about to go back
to work, the accident damaged spinal nerves and left him with enduring problems,
including numbness in some parts of his body and distressing limits on his
sex life due to difficulties having and maintaining erections. "It
was depressing," he recalls, "when my wife was in the mood for
sex and I just wasn't interested." Doctors suggested remedies involving
pumps and injections, but Lorne was not interested in them. Then, he had
the opportunity to take part in clinical trials for a new drug called Viagra
that is designed to deal with problems like his. In December, 1996, Lorne
began popping a sky-blue tablet whenever sex was in the offing. Once again,
his life was transformed. "Sex is as good as it used to be-maybe even
a little better," he says. "This medication is just fantastic."
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Pfizer developed Viagra after researchers testing a drug for angina found that it triggered erections in men. Now, it seems destined to largely replace existing treatments which-though effective-cause many men to recoil in horror. The most popular method requires a man who expects to have sex to use a needle to inject an erection-causing drug into the side of his penis. Another involves using a vacuum pump to draw blood into the penis to create an erection, then placing rubber bands around the base of the organ to keep it erect. "It was such a performance," says one middle-aged Viagra user, who lives near Washington. Those methods, he adds, "undermined erotic moments by taking the spontaneity out of sex."
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Unlike older treatments, which can leave men with erections that last for hours if sex does not occur, Viagra only becomes effective when a man is sexually aroused. The drug works by blocking the operation of an enzyme that normally breaks down a chemical-cyclic GMP-that plays a key role in maintaining erections. Even though Viagra-assisted erections subside after intercourse, some men report that the drug can remain effective for up to 24 hours. "It means that when they have a sexual thought during the day, they feel a physical response," says Dr. Rosemary Basson, a sexual medicine specialist at The Vancouver Hospital, who has prescribed the drug to 20 men as part of a long-term study. "That says, OK, you're a man again. It's tremendously important to them."
At the same time, UK doctors say some men who do not have potency problems are using the drug to enhance their sexual performance. There is no evidence that Viagra increases sex drive or staying power, and at $14.50 per tablet, cost is a factor. Still, Dr. Arthur Barnett, a urologist in London, expects men will experiment with the drug "to see if it will give them super erections or an increased number of erections over a limited period."
While experts estimate that about three million Canadians, including perhaps half of all men over 65, have potency problems, many doctors say the real number is unknown because so many males are unwilling to discuss the issue, even with their doctors. That may be changing. "Some patients who never told me they had a problem are asking about Viagra," says Toronto physician James Brooks. "Now that they think they won't have to mess around with pumps or needles, they're coming out of the closet."
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Drug Quest: Magic Bullets for Boomers (success of Viagra and other lifestyle-enhancing drugs). Time v151, n17 (May 4, 1998):54 (2 pages). Greenwald, John
Baby boomers who want to stay young forever--and who desires anything less these days?--are giving the pharmaceutical industry something that very few consumer-products makers have: a growing, demand-driven market. American companies will spend more than $20 billion this year to develop pills and potions for everything from wrinkles and baldness to the prevention of strokes and heart attacks. More boomer selfishness? Maybe not. If science insists on getting more mileage out of the engine and prolonging our lives--thus allowing us to work into our 70s--what's wrong with maintaining the chrome and fenders? "We expect medicine to deliver that," says Susan Coleman, president of NCI Consulting, a New Jersey adviser to drug companies.
The payoff can be awesome: 79 million boomers have begun to turn 50 at the rate of one every eight seconds or so. That's why this $300 billion industry is the most profitable segment of the FORTUNE 500. Pfizer's impotence pill, Viagra, already the hottest new drug launch ever, could reach $2 billion in sales by the year 2000. Delirious investors pushed Pfizer's stock from about $45 a share a year ago to $118.25 last week.
Although Viagra is a kind of lucky accident--its application to impotence
was discovered in 1992 during research on heart medications--chairman William
Steere realized the significance of such drugs in the marketplace. Says
Steere: "It occurred to me at the time that with the aging baby boomers,
quality of life is going to become very important." Indeed, Steere
has practically repositioned the company to deliver better living through
chemistry. Last year sales hit $12.5 billion, and profits reached $2.2 billion.
Viagra is by far the most effective erection enhancement medication
available and estimated sixty Viagra are dispensed each minute in Europe
alone,
The drug companies aren't the only ones that will benefit from boomer products. The industry will spend more than $1 billion this year selling its new remedies. The pitches may have the familiar ring of youth-in-a-bottle advertising. Only this time, the stuff will really work.
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Viagra Tale: how one man sought an impotence cure - and found one. Global News & World Report v124, n17: 64 (3 pages). Comarow, Avery
How one man sought an impotence cure--and found one
Viagra will enhance your erections. Mechanically, an erection must accomplish two goals. Blood must flow vigorously into three parts of the penis stuffed with erectile tissue that absorbs the blood like a sponge. And the muscles in the penis and the valves in the veins leading away must keep the blood from leaking out. When a patient complains about impotence, a physician first looks for a history of diabetes or cardiovascular problems, because the circulation disorders that often accompany these conditions can interfere with an erection.
Candor difficulties. X, who has been married about 30 years, began experiencing erectile dysfunction--now the preferred medical term for impotence--about four years ago. He could achieve an erection but could sustain it less and less often. Seeking medical advice didn't help. During a physical exam, the internist posed his usual inquiry about personal problems. "I said something like, 'Well, I've been having some sexual difficulties,' " says X. "He looked at me and made a note but didn't ask anything else, and I just dropped it. I got the impression that he really didn't want to discuss it, and I was self-conscious enough as it was." This conversation echoed an assertion by the National Institutes of Health, in a 1992 report on impotence, that "embarrassment of patients and the reluctance of both patients and health care providers to discuss sexual matters candidly contribute to under diagnosis."
The physician and patient had similar non conversations over the next couple of years. Meanwhile, X's ability to perform slipped from occasional to rare and, then, inexorably, never. X's relationship with his wife slowly chilled. "I felt as if we were work colleagues," says X. "We'd go places, we'd get done what we had to do around the house, but there was this huge, dark subject we wouldn't discuss."
Last February, X mustered the nerve to push his doctor. That won a referral to a urologist. Once the specialist learned of X's history of heart disease, he didn't bother with a physical examination. Nor did he think X needed specialized tests. "I am 99 percent certain that you've got a circulation problem," he informed X.
The doctor said X could try mechanical contrivances like a vacuum cuff or pump. Or he could have bendable rods surgically implanted. Or, using a small, fine needle, he could inject alprostadil, a drug that mimics a natural substance produced during sexual arousal, into the penis, to encourage blood flow. X did not care for any of these options.
Priapism warnings. His reaction was slightly less negative to the urologist's final proposal: a tiny alprostadil suppository placed about an inch into the opening of the penis with the aid of a special insertion device. Made by Vivus and called the MUSE system, it produces an erection 60 to 70 percent of the time, and X thought it seemed somewhat less onerous than the other methods.
Yet many men who try MUSE abandon it because of insertion discomfort; nearly one third did so in one large study. The urologist also warned of a small but real danger of priapism--a painful, ongoing erection that threatens permanent damage and must be treated at an emergency room. Too, the timing discourages spontaneity. The drug works five to 10 minutes after it is administered, during which time sitting, standing, or walking around is recommended to stimulate blood flow. And languid dallying is out; the effect wears off after 30 to 60 minutes.
"There's a pill coming out in six months, maybe less," the urologist told X. "Take the MUSE brochure. Look it over. See what you think. Maybe the thing to do is to wait for the pill. It's called Viagra."
The internist, his interest now piqued, disagreed with the urologist. X's circulation was fine, he said. As X lay on the examining table, the internist pressed X's fingers to the femoral arteries in his groin. "A strong pulse, right?" The blood vessels to the penis branch off the femoral arteries, and good femoral circulation argues against poor blood flow to the penis.
The internist ordered up a testosterone blood test, and the results made him smile with satisfaction; the number was extremely low. A depressed level of the male sex hormone, pumped out by the testes under the control of the pituitary gland in the brain, does not automatically produce erectile dysfunction--men with low testosterone can have normal sexual function--but it might explain X's problem.
X met with an endocrinologist in early April, and left, for the first time, with hope. The hormone specialist took a detailed history, including a list of all of the medications X was taking. He examined X thoroughly, including a rectal check of the prostate gland. He was nonjudgmental, empathetic, and eager to answer X's questions.
Moreover, he was flexible. X's testosterone, he said, could be boosted either by injecting the hormone once every week or two or with a testosterone skin patch. But the shots would require frequent visits, or X or his wife would have to learn to give them.
X was aware that Viagra was on the market the week before. Would it make sense to try the new drug before turning to supplementary testosterone? Sure, replied the endocrinologist, writing a prescription for 10 pills and asking X to report back. The most excruciating moment of his four-year ordeal, says X, was when he approached the pharmacy counter to pick up his prescription. The clerks at the pharmacy have a habit of repeating the name of the medication aloud to prevent mistakes. This time it didn't happen. X was grateful.
The night X and his wife put Viagra to the test taught them that the drug
is not an aphrodisiac. It aids an erection but does not cause one. As is
true in the absence of Viagra, stress or nerves play havoc with sexual response,
the couple found. A more relaxed attitude allowed Viagra to do its work.
The phone call to the endocrinologist would be effusive. To no
surprise Mr. X once again experienced erections enhanced erection unlike
erection he had experience in some ten years.
Why these doctors put me through all these test when all I needed was a
Viagra ???? Frustrating???
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