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Levitra
(vardenafil) mechanism of action is similar to
Viagra in erectile dysfunction drug. Viagra was the first of the so called,
"PDE-5 inhibitors" and Levitra is known in the same class to significantly
help individuals treat their erectile dysfunction (impotence). Similar to
Viagra, Levitra increases the quantity of blood supplied to the penis thus
improving the erection. Levitra is very selective in inhibiting the PDE-5
without affecting other isoenzymes. This allows a smaller dose of Levitra to
have a more pronounced effect as a larger dose of Viagra (the standard dose
of Levitra dose is 10mg while the standard dose of Viagra dose is 50mg).
Through this action, smooth muscle in the penis remains relaxed for a longer
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the penis thereby generating an erection. Levitra is unique in that it
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stimulation will an erection occur.
More specifically, Penile erection is a haemodynamic process. During sexual stimulation, nitric oxide is subsequently released. The nitric acid activates an enzyme guanylate cyclase, resulting in an increased level of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. This results in smooth muscle relaxation in the penis, allowing increased inflow of blood into the penis. The level of cGMP is regulated by the rate of synthesis via guanylate cyclase and by the rate of degradation via cGMP hydrolysing phosphodiesterases (PDEs).
Levitra is a potent and
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Levitra enhances the effect of endogenous
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inhibition of PDE5 by Levitra results in increased corpus cavernosum levels
of cGMP. Sexual stimulation is required for Levitra to produce its
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- Levitra improves the duration, hardness, and the ability
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- Some men report the positive effects (erectile dysfunction drug) of Levitra for as long as twenty-four hours
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- Levitra is effective in treating
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- Levitra as proven to be effective in many men who did
not experience positive results using Viagra.
- Levitra
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prostate cancer surgery and in those individuals who
have other preexisting medical conditions e.g. diabetes.
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Levitra increases a naturally occurring process. Therefore, only through sexual stimulation will an erection occur. Once a man experiences sexual stimulation, Levitra increase the blood flow to the penis, enhancing both the length and the girth of the penis. Most men notice an enhanced erection within 20-30 minutes of their initial dose of Levitra. Some men reports the enhanced erections recurring up to 24 hours from taking a single dose of Levitra.
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